Neurology Practice Questions
Neurology spans stroke management, seizure disorders, headache syndromes, and neurodegenerative disease — high-yield on the MCCQE, USMLE Step 2 CK, and PLAB. These four sample questions come from MediLingo's bank of 3,900+ questions across 21 specialties.
Sample questions
Question 1
A 45-year-old man has steadily progressive spastic paraparesis over 3 years without discrete relapses. MRI shows spinal cord demyelination. What MS course is this?
a) Primary progressive MS ✓ Correct
b) ALS
c) Secondary progressive MS
d) Relapsing-remitting MS
Key teaching point: Primary progressive MS: steady progression from onset, no relapses — often spinal.
Question 2
A patient with aneurysmal SAH has a 7mm anterior communicating artery aneurysm. What is the definitive management to prevent rebleeding?
a) Anticoagulation
b) Lumbar drain alone
c) Observation with serial imaging
d) Secure the aneurysm by surgical clipping or endovascular coiling ✓ Correct
Key teaching point: Ruptured aneurysm must be secured early by clipping or coiling to prevent rebleeding.
Question 3
What is the genetic basis of Huntington disease?
a) X-linked
b) Autosomal dominant CAG trinucleotide repeat expansion ✓ Correct
c) Mitochondrial
d) Autosomal recessive point mutation
Key teaching point: Huntington's: autosomal dominant CAG repeat in HTT — anticipation, worse with paternal transmission.
Question 4
A migraine patient uses sumatriptan 12 days per month and now has daily headaches. What is the diagnosis?
a) Chronic tension headache
b) Brain tumor
c) Idiopathic intracranial hypertension
d) Medication-overuse headache ✓ Correct
Key teaching point: Medication-overuse headache: triptans >=10 days/month or analgesics >=15 days/month — withdraw the drug.
Keep going — 3,900+ questions
With streaks, XP and duels. Free for med students in 72 countries; 30-day free trial elsewhere.
More practice questions
- Nephrology — AKI, CKD, electrolytes, acid-base, and glomerular disease
- Hematology — Anemias, coagulation disorders, leukemias, and lymphomas
- MSK & Rheumatology — Arthritis, fractures, metabolic bone disease, and vasculitis
- Infectious Disease — Endocarditis, HIV, UTIs, sepsis, and tropical infections
- General Surgery — Biliary disease, breast, thyroid, and perioperative care
- Biostatistics & Epidemiology — Risk reduction, study design, confidence intervals, and screening
- Dermatology — Inflammatory dermatoses, infections, and skin manifestations
- Ophthalmology — Red eye, acute vision loss, and glaucoma
- ENT — Epistaxis, otitis media, croup, and pharyngeal infections
- Geriatrics & Palliative Care — Falls, delirium, dementia, capacity, and end-of-life
- Psychiatry — Mood disorders, anxiety, psychosis, and substance use
© 2026 MediLingo. For educational purposes only. Questions are AI-generated and multi-layer reviewed.